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GEMM™ for Pigs

 

We combat post-weaning diarrhea in piglets by developing GEMM™ solutions, enhancing gut health and reducing economic losses in pork production.

Understanding

Post-Weaning Diarrhea

Weaning is one of the most stressful events in an early pig’s life, and during this stage their gastrointestinal immunity is still underdeveloped, making them vulnerable to intestinal and immune dysfunction.¹ Unfortunately, an increasing incidence of post-weaning diarrhea (PWD) in piglets has been observed worldwide, irrespective of industrialization or climate conditions. PWD is often caused by the pathogenic bacteria enterotoxigenic Escherichia coli (ETEC).²'³ ETEC bacteria has an enhanced ability to colonize the intestinal tract and outcompete the normal/beneficial bacteria that live in the gut. ETEC also produces enterotoxins, which lead to the profuse diarrhea and systemic symptoms observed in piglets.²'⁴ PWD has a high mortality rate (20-30%) and the severe diarrhea, appetite loss, dehydration, and weight loss often result in growth issues for piglets who do survive.

Preventative strategies currently used in the industry include addition of probiotics, antibiotics, inorganic and organic acids into their feed. However, these strategies show inconsistent results in preventing/controlling PWD.⁵⁻⁷

Our objective is to create a consortium of GEMM™ that are specifically designed for pigs to keep PWD-inducing pathogens under control and help piglets thrive during the stress of weaning. 

Our GEMM™ Solutions for Piglet Health

Certain bacteria produce “bacteriocins”, which are toxins that target other bacteria in the gut. The BioPersist™ and BioColonize™ technologies developed by Melius MicroBiomics have been incorporated into specific bacteria that inherently possess the ability to produce these bacteriocins and have shown to inhibit diarrhea-inducing bacteria such as E. coli strains and Salmonella enterica.⁸'⁹

 

Our objective is to create a consortium of GEMM™ that are specifically designed for pigs to keep PWD-inducing pathogens under control and help piglets thrive during the stress of weaning. By aiding in the piglet transition into the new environment, we hope to prevent massive economic losses that are currently incurred by pork producers worldwide.

Pig gut graphic
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